Karlin S, Carmeli D
Proc Natl Acad Sci U S A. 1974 Dec;71(12):4727-31. doi: 10.1073/pnas.71.12.4727.
The evolutionary behavior of a diploid population characterized by a trait determined at one or two major loci subject to the combined effects of artificial and natural selection pressures is investigated. A number of different genotypic phenotypic associations are set forth, including additive allelic effects and additive loci effects with a variety of culling programs. Threshold selection schemes as well as culling favoring intermediate phenotypic values are considered. For these formulations results are reported concerning the dynamic progress of the population, a delineation of the numbers and properties of the stable equilibria outcomes, and a discussion of their qualitative and quantitative dependence on the two kinds of selection forces. The level of culling can be used as a control through which natural selection parameters can be estimated.
研究了一个二倍体种群的进化行为,该种群的一个性状由一两个主要基因座决定,受到人工选择压力和自然选择压力的综合影响。提出了许多不同的基因型-表型关联,包括加性等位基因效应和具有各种淘汰方案的加性基因座效应。考虑了阈值选择方案以及有利于中间表型值的淘汰。对于这些公式,报告了关于种群动态进展的结果、稳定平衡结果的数量和性质的描述,以及它们对两种选择力的定性和定量依赖性的讨论。淘汰水平可以用作一种控制手段,通过它可以估计自然选择参数。