Siegel J H, Berger S A, Sable R A, Ho R, Rosenthal W S
Am J Gastroenterol. 1979 May;71(5):465-8.
Fifty patients (29 females) undergoing ERCP were studied prospectively for the occurrence of bacteremia associated with this endoscopic procedure. Each patient had blood samples drawn for aerobic and anaerobic cultures before endoscopy, after entering the duodenum, 5 and 15 minutes after cannulation of the papilla of Vater. Subcultures were made at 24 and 48 hours for a total of 1,200 cultures. No positive cultures were obtained in 48 patients. One patient developed a Staphylococcus epidermidis bacteremia during the procedure. The cleansing technic for the instruments consisted of alcohol and water only. Prophylactic antiobiotics were not administered. In contrast to other gastrointestinal procedures, our results suggest that bacteremia is an uncommon occurrence in ERCP despite the longer duration of the procedure and instrumentation of a sterile duct system.
对50例接受内镜逆行胰胆管造影术（ERCP）的患者进行了前瞻性研究，以观察与该内镜操作相关的菌血症发生情况。每位患者在内镜检查前、进入十二指肠后、乳头插管后5分钟和15分钟采集血样进行需氧和厌氧培养。在24小时和48小时进行传代培养，共培养1200次。48例患者培养结果为阴性。1例患者在操作过程中发生表皮葡萄球菌菌血症。器械清洁技术仅包括酒精和水。未使用预防性抗生素。与其他胃肠道操作不同，我们的结果表明，尽管ERCP操作时间较长且涉及无菌管道系统的器械操作，但菌血症在ERCP中并不常见。
