Lavery J P, Miller C E
Am J Obstet Gynecol. 1979 Jun 15;134(4):366-75. doi: 10.1016/s0002-9378(16)33077-0.
This paper presents a review of physical principles involved in deformation and creep in the human chorioamniotic membrane. These are definable rheological properties found in many materials. Experimental data are presented on 66 human fetal membranes. A difference in the stress tolerance between preterm and term membranes is demonstrated. A computer model has been devised which allows for the calculation of changes in thickness of the membrane at the point of fracture. This computer model allows for the study of the physical property of the tissue in ways which have not previously been suggested. The model suggests that the pathophysiology related to rupture of the membrane is based on changes in the thickness of this tissue occurring secondary to acute and chronic stress applications. The data derived in these experiments suggest a possible physical model for rupture of the membranes; they also introduce questions regarding the anatomic and biochemical makeup of the chorion and the amnion and the respective role that each plays in maintaining the integrity of the human chorioamniotic sac.
本文综述了人类绒毛羊膜的变形和蠕变所涉及的物理原理。这些是许多材料中都存在的可定义流变学特性。文中给出了66份人类胎膜的实验数据。结果表明早产胎膜和足月胎膜在应力耐受性上存在差异。已经设计了一个计算机模型，该模型可以计算胎膜破裂点处的厚度变化。这个计算机模型能够以前所未有的方式研究组织的物理特性。该模型表明，与胎膜破裂相关的病理生理学是基于急性和慢性应激作用后该组织厚度的变化。这些实验得出的数据提示了一个可能的胎膜破裂物理模型；它们还引发了关于绒毛膜和羊膜的解剖学和生化组成以及它们各自在维持人类绒毛羊膜囊完整性中所起作用的问题。
