Schober E A, Kusy R P, Savitz D A
Department of Biomedical Engineering, University of North Carolina, Chapel Hill 27599.
Ann Biomed Eng. 1994 Sep-Oct;22(5):540-8. doi: 10.1007/BF02367090.
To further the characterization of the chorioamniotic membrane's physical properties, we assessed its ability to withstand a concentrated force. Probes of various diameters were used to puncture 275 specimens from 11 membranes. Values for "strength"/thickness, "stiffness"/thickness, and "toughness"/thickness all showed positive linear correlations (p < 0.001) with the increase of d/D, the ratio of probe diameter to specimen diameter. "Ductility" was independent of diameter, though a logarithmic regression did fit the data marginally (p < 0.05). The separate fracture of the amnion and chorion, which is reflected in ductility measurements, results in an increase in the distance the membrane can be deflected in vitro. In vivo, this behavior would translate to a reduction of pressure exerted on the remaining membrane, while the integrity of the protective sac is maintained. The data pool of mechanical characteristics was enlarged by reconciling data that were gathered by either of two testing methods: puncturing or bursting; the latter method involves the application of force over the entire surface of the test specimen.
为进一步了解羊膜绒毛膜的物理特性，我们评估了其承受集中力的能力。使用各种直径的探针穿刺来自11个胎膜的275个样本。“强度”/厚度、“刚度”/厚度和“韧性”/厚度的值均与探针直径与样本直径之比d/D的增加呈正线性相关（p<0.001）。“延展性”与直径无关，不过对数回归勉强符合数据（p<0.05）。羊膜和绒毛膜的分离断裂反映在延展性测量中，这会导致胎膜在体外可偏转距离的增加。在体内，这种行为将转化为施加在剩余胎膜上的压力降低，同时保持保护囊的完整性。通过整合两种测试方法（穿刺或破裂）收集的数据，扩大了力学特性的数据库；后一种方法涉及在测试样本的整个表面施加力。
