Anatkov A, Dobreva A, Noev K, Meshkov T, Velizarova K
Vutr Boles. 1974;13(6):93-100.
The morphological hemogram peculiarities are described in 10 patients with acute leukosis (nine with myeloblastoid variance and one with monocytoid variance of acute leukosis). Leukemic hiatus is not to be found in all the patients and besides paramyeloblasts--granular "filamented neutrophils" are present in the peripheral blood in considerable absolute values. Cytomorphologic, cytochemical and electron microscopic investigations were carried out on those "paraneutophils". Complex data for pathological leukosis characteristics of those cells were established that differed them from the normal cells. In five of the patients--definite data for acute leukosis were obtained with the histomorphological investigation of the blood tissue, in that way excluding primary myeloblast phase of myeloleukosis. Conclusions were drawn that those cells ("paraneutrophils") have the same prognostic value in peripheral blood as paramyeloblasts and are not affected by polychemical therapy. This was stressed to be a more particular variance of acute leukosis.
描述了10例急性白血病患者（9例为急性白血病的成髓细胞样变异型，1例为单核细胞样变异型）的形态学血常规特点。并非所有患者均有白血病裂孔，且除早幼粒细胞外，外周血中还存在绝对值可观的颗粒状“丝状中性粒细胞”。对这些“类中性粒细胞”进行了细胞形态学、细胞化学和电子显微镜检查。确立了这些细胞白血病病理特征的综合数据，使其与正常细胞有所区别。5例患者通过血液组织的组织形态学检查获得了急性白血病的确切数据，从而排除了骨髓白血病的原代成髓细胞阶段。得出的结论是，这些细胞（“类中性粒细胞”）在外周血中的预后价值与早幼粒细胞相同，且不受多药化疗的影响。强调这是急性白血病一种更为特殊的变异型。
