Biddulph J, Woodfield D G
P N G Med J. 1974 Dec;17(4):364-72.
Neonatal jaundice is a common problem in Port Moresby. A survey was carried out on 50 consecutive jaundiced neonates in an attempt to delineate the causes of severe neonatal jaundice (bilirubin 15 mg. % or more). ABO blood group incompatibility, G-6-P-D deficiency and infection accounted for 62% of cases while no cause could be found in 38% of cases. Low birth weight, multiple births, male sex, asphyxia, delivery occuring outside the hospital, and vacuum extraction were associated more commonly with jaundiced neonates than with the controls. There was a statistically significant association between the use of promethazine in the mother during and after labour and jaundice in the newborn. The association between the use of sulphonamides in the mother after delivery and neonatal jaundice was suggestive but not statistically significant.
新生儿黄疸是莫尔斯比港的一个常见问题。对50例连续的黄疸新生儿进行了一项调查,以确定严重新生儿黄疸(胆红素15毫克%或更高)的病因。ABO血型不合、葡萄糖-6-磷酸脱氢酶(G-6-P-D)缺乏和感染占病例的62%,而38%的病例未发现病因。低出生体重、多胎、男性、窒息、院外分娩和真空吸引与黄疸新生儿的关联比与对照组更为常见。分娩期间及产后母亲使用异丙嗪与新生儿黄疸之间存在统计学上的显著关联。产后母亲使用磺胺类药物与新生儿黄疸之间的关联具有提示性,但无统计学意义。