Ross D, Sutton R, Dow J, Gonzalez-Lavin L, Hendrix G, Jefferson K, McDonald L, Petch M, Smithen C, Sowton E
Br Med J. 1972 Jun 10;2(5814):644-8. doi: 10.1136/bmj.2.5814.644.
Sixty-seven patients have had aortocoronary venous graft bypass surgery by one surgeon for the relief of symptoms of severe coronary heart disease, including eight emergency operations. The overall operative, hospital, and late mortality was low in patients with favourable myocardial function and no previous myocardial infarction. There was a 7% mortality in patients with a normal preoperative chest radiogram, 8% mortality when the left ventricular end-diastolic pressure was normal preoperatively, and a 5% mortality in patients who had normal left ventricular angiograms. The overall mortality in all elective operations for cardiac pain resistant to medical treatment was 15.8%. 89% of survivors improved; 67% are pain-free. Exercise tolerance in survivors is increased by 135%, atrial pacing results are improved by 10%. Left ventricular end-diastolic pressure is unchanged. Left ventricular function on angiography is improved. The improvement in left ventricular function assessed objectively correlates positively with vein-graft patency, as does freedom from angina pectoris.
67例患有严重冠心病症状的患者接受了由一位外科医生进行的主动脉冠状动脉静脉搭桥手术,其中包括8例急诊手术。对于心肌功能良好且既往无心肌梗死的患者,总体手术、住院及晚期死亡率较低。术前胸部X线片正常的患者死亡率为7%,术前左心室舒张末期压力正常的患者死亡率为8%,左心室血管造影正常的患者死亡率为5%。所有因药物治疗无效的心脏疼痛而进行的择期手术的总体死亡率为15.8%。89%的幸存者病情有所改善;67%的患者无痛。幸存者的运动耐量提高了135%,心房起搏效果改善了10%。左心室舒张末期压力未变。血管造影显示左心室功能有所改善。客观评估的左心室功能改善与静脉移植物通畅性呈正相关,与无心绞痛也呈正相关。