通过胰蛋白酶消化使赖氨酸加压素的行为和内分泌效应解离。
Dissociation of the behavioural and endocrine effects of lysine vasopressin by tryptic digestion.
作者信息
de Wied D, Greven H M, Lande S, Witter A
出版信息
Br J Pharmacol. 1972 May;45(1):118-22. doi: 10.1111/j.1476-5381.1972.tb09582.x.
Abstract
- Lysine vasopressin induces resistance to extinction of active avoidance behaviour (De Wied, 1971).2. Digestion of lysine vasopressin with trypsin almost completely destroys the pressor-, antidiuretic-, oxytocic- and corticotrophin-releasing factor activities of lysine vasopressin, but does not materially influence its effect on the maintenance of an avoidance response.
摘要
赖氨酸加压素可诱导对主动回避行为消退的抗性（德维德，1971年）。
用胰蛋白酶消化赖氨酸加压素几乎可完全破坏其加压、抗利尿、催产和促肾上腺皮质激素释放因子活性，但对其维持回避反应的作用影响不大。
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