Malone J M, Moore W S, Goldstone J, Malone S J
Ann Surg. 1979 Jun;189(6):798-802. doi: 10.1097/00000658-197906000-00018.
The experience with 142 below-knee amputations for vascular occlusive disease and/or diabetes mellitus in 133 patients has been reviewed. The program utilized Xenon(133) skin bloodflow measurement for the selection of amputation level, emphasized the use of the long posterior skin flap as an important part of surgical technique, and employed immediate postoperative prosthesis with accelerated rehabilitation for postoperative management. The results of this program yielded a 0% postoperative mortality, 89% amputation healing, and 100% prosthesis rehabilitation of all unilateral below-knee amputees, and 93% rehabilitation of all bilateral below-knee amputees. The average time interval between amputation and fitting of a permanent prosthesis was 32 days. The use of Xenon(133) clearance as a measurement of capillary skin bloodflow for purposes of amputation level selection continues to be valid. All amputations with flows in excess of 2.6 ml/100 g tissue/min healed primarily, including the last 58 consecutive amputations. The total amputation of the 172 hospital V.A. system was surveyed and a cost analysis, based upon duration of postamputation hospitalization, comparing immediate postoperative prosthesis with conventional techniques, was performed. The savings to the system, taking into account start-up and maintenance costs for a program which employs immediate postoperative prosthesis, was projected to be $80,000,000 over five years. We conclude that a modern amputation program employing Xenon(133) clearance for amputation level selection and immediate postoperative prosthesis with accelerated rehabilitation is well justified based upon reduced morbidity, negligable mortality, and optimum patient prosthetic rehabilitation at a marked reduction in overall cost.
回顾了133例患者142次因血管闭塞性疾病和/或糖尿病进行的膝下截肢手术的经验。该方案利用氙(133)皮肤血流测量来选择截肢平面,强调使用长后皮瓣作为手术技术的重要组成部分,并采用术后即刻安装假肢并加速康复进行术后管理。该方案的结果显示术后死亡率为0%,截肢愈合率为89%,所有单侧膝下截肢者的假肢康复率为100%,所有双侧膝下截肢者的康复率为93%。截肢与安装永久性假肢之间的平均时间间隔为32天。使用氙(133)清除率作为毛细血管皮肤血流的测量方法来选择截肢平面仍然有效。所有血流超过2.6 ml/100 g组织/分钟的截肢均一期愈合,包括最后连续的58例截肢。对172家退伍军人医院系统的截肢情况进行了调查,并基于截肢后住院时间进行了成本分析,比较了术后即刻安装假肢与传统技术。考虑到采用术后即刻安装假肢方案的启动和维护成本,预计该系统在五年内可节省8000万美元。我们得出结论,基于发病率降低、死亡率可忽略不计以及患者假肢康复效果最佳且总体成本显著降低,采用氙(133)清除率选择截肢平面并术后即刻安装假肢并加速康复的现代截肢方案是完全合理的。