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马(Heq2Neq2)流感病毒的抗原变异

Antigenic variation of equine (Heq2Neq2) influenzavirus.

作者信息

Pereira H G, Takimoto S, Piegas N S, do Valle L A

出版信息

Bull World Health Organ. 1972;47(4):465-9.

Abstract

Influenza equine (Heq2Neq2) strains isolated during the course of epizootics observed in Guanabara (Rio de Janeiro) and São Paulo, Brazil, in July-October 1969 were shown to differ antigenically from earlier strains of the same subtype (A/equine/Miami/1/63 (Heq2Neq2)). The difference could be clearly demonstrated in haemagglutination inhibition tests performed with postinfection horse or ferret sera but not with hyperimmune rooster sera. Antibody responses of diseased horses were higher and more frequent against current isolates than against strain equine/Miami/1/63. Some animals also showed antibody responses to the Hong Kong variant of human influenzavirus A.

摘要

1969年7月至10月在巴西里约热内卢的瓜纳巴拉和圣保罗发生动物流行病期间分离出的马流感(Heq2Neq2)毒株,在抗原性上与同一亚型的早期毒株(A/equine/Miami/1/63 (Heq2Neq2))不同。这种差异在用感染后马或雪貂血清进行的血凝抑制试验中可以清楚地显示出来,但用超免疫公鸡血清则不能。患病马对当前分离株的抗体反应比对马/迈阿密/1/63株的反应更高且更频繁。一些动物还显示出对甲型人流感病毒香港变种的抗体反应。

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