Ruben F L, Smith E A, Foster S O, Casey H L, Pifer J M, Wallace R B, Atta A I, Jones W L, Arnold R B, Teller B E, Shaikh Z Q, Lourie B, Eddins D L, Doko S M, Foege W H
Bull World Health Organ. 1973;48(2):175-81.
Children receiving smallpox, measles, and yellow fever vaccines simultaneously at separate sites responded adequately to all three vaccines. In those children, 9 months of age and older, who received these three vaccines in addition to diphtheria-pertussis-tetanus vaccine, there was a decrease in measles seroconversion rates from 89% to 70%. Possible interactions between live and killed vaccines should be considered when the administration of multiple antigens is planned.
在不同部位同时接种天花、麻疹和黄热病疫苗的儿童对这三种疫苗均有充分反应。在9个月及以上的儿童中,除了接种白喉-百日咳-破伤风疫苗外还接种这三种疫苗,其麻疹血清转化率从89%降至70%。在计划接种多种抗原时,应考虑活疫苗和灭活疫苗之间可能存在的相互作用。