Chandra S R, Friedman E
Arch Ophthalmol. 1979 Jul;97(7):1331-2. doi: 10.1001/archopht.1979.01020020073017.
The effect of vasodilators on choroidal blood flow (CBF) was studied by the krypton clathrate Kr 85 desaturation technique in anesthetized cats. Niacin, papaverine hydrochloride, phentolamine mesylate, and tolazoline hydrochloride were injected via the lateral long posterior ciliary artery (LLPCA) and the femoral artery. The systemic administration of these drugs via the femoral artery, in the doses used, had no significant effect on mean arterial pressure, choroidal vascular resistance (CVR), or CBF. Local administration of the same agents via the LLPCA caused a decrease in CVR with a corresponding increase in CBF.
采用氪笼形化合物Kr 85去饱和技术，在麻醉猫身上研究了血管扩张剂对脉络膜血流（CBF）的影响。通过睫状后长动脉外侧支（LLPCA）和股动脉注射烟酸、盐酸罂粟碱、甲磺酸酚妥拉明和盐酸妥拉唑啉。通过股动脉全身给药这些药物，在所使用的剂量下，对平均动脉压、脉络膜血管阻力（CVR）或CBF没有显著影响。通过LLPCA局部给药相同药物会导致CVR降低，同时CBF相应增加。
