福尔马林处理疫苗和辐照疫苗预防钩端螺旋体病的对比试验。
Comparative tests with formolized and irradiated vaccines against leptospirosis.
作者信息
Babudieri B, Castelli M, Pisoni F
出版信息
Bull World Health Organ. 1973 May;48(5):587-90.
The effectiveness of gamma-irradiated antileptospirosis vaccines and of vaccines killed with formol was compared in guineapigs. Irradiated vaccines proved no more effective than formolized vaccines in preventing either death or persistent kidney infection. Anti-pomona vaccines gave little protection against serotype icterohaemorrhagiae, and there was no significant difference between irradiated and formolized preparations. Vaccine prepared from a virulent strain showed little advantage over vaccine prepared from weak strains.
在豚鼠身上比较了γ射线辐照抗钩端螺旋体疫苗和甲醛灭活疫苗的效果。结果表明，在预防死亡或持续性肾脏感染方面，辐照疫苗并不比甲醛灭活疫苗更有效。抗波摩那型疫苗对黄疸出血型血清型几乎没有保护作用，辐照制剂和甲醛灭活制剂之间没有显著差异。由强毒株制备的疫苗与由弱毒株制备的疫苗相比优势不大。
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