钩端螺旋体病免疫接种：用热灭活全细胞和外膜抗原在仓鼠身上进行的疫苗试验。
Immunization against leptospirosis: vaccine trials with heat-killed whole cell and outer envelope antigens in hamsters.
作者信息
Zeigler J A, Jones R H, Kubica K
出版信息
Bull Pan Am Health Organ. 1976;10(2):126-30.
PMID:974302
Abstract
Heat-killed whole cell and outer envelope antigens prepared from homologous virulent and avirulent strains of Leptospira serotypes canicola and pomona were evaluated for protecting hamsters against experimental leptospirosis. The heat-killed bacterins proved at least as effective as the outer envelope antigens, or more so, in providing protection against death and infection, and they are easier and more economical to prepare.
摘要
对从钩端螺旋体血清型犬型和波摩那型的同源有毒和无毒菌株制备的热灭活全细胞和外膜抗原进行了评估，以保护仓鼠免受实验性钩端螺旋体病的侵害。事实证明，热灭活菌苗在预防死亡和感染方面至少与外膜抗原一样有效，甚至更有效，而且制备起来更容易、更经济。
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