St John D J, Masterton J P, Yeomans N D, Dudley H A
Br Med J. 1974 Jan 26;1(5899):140-3. doi: 10.1136/bmj.1.5899.140.
A policy of immediate investigation of patients with haematemesis or melaena or both led to the diagnosis of the Mallory-Weiss syndrome in 16 out of 121 patients admitted to a combined medical-surgical unit over three and a half years. A typical history suggestive of the diagnosis was obtainable in only nine of the 16 patients, though recent alcohol intake was high in another four. All patients survived the episode. Establishment of the diagnosis by oesophagogastroscopy was of special benefit when surgery was needed for control of continuing blood loss, but it also simplified the subsequent medical management of those patients in whom bleeding stopped spontaneously. The incidence of 13.2% in this series suggests that the Mallory-Weiss syndrome may be a relatively common cause of upper gastrointestinal bleeding.
在三年半的时间里，对一家内外科联合病房收治的121例患者采取了对呕血或黑便或两者兼具的患者立即进行检查的政策，结果在其中16例患者中诊断出了马洛里-魏斯综合征。16例患者中只有9例有提示该诊断的典型病史，不过另外4例近期饮酒量很大。所有患者此次发作后均存活。当需要手术控制持续失血时，通过食管胃镜检查确诊特别有用，但这也简化了那些出血自行停止的患者随后的内科治疗。本系列中13.2%的发病率表明，马洛里-魏斯综合征可能是上消化道出血相对常见的原因。
