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The mechanism of action of ethanolamine ammonia-lyase, a B12-dependent enzyme. The reversible formation of 5'-deoxyadenosine from adenosylcobalamin during the catalytic process.

作者信息

Babior B M, Carty T J, Abeles R H

出版信息

J Biol Chem. 1974 Mar 25;249(6):1689-95.

PMID:4544750
Abstract
摘要

相似文献

1
The mechanism of action of ethanolamine ammonia-lyase, a B12-dependent enzyme. The reversible formation of 5'-deoxyadenosine from adenosylcobalamin during the catalytic process.
J Biol Chem. 1974 Mar 25;249(6):1689-95.
2
The mechanism of action of ethanolamine ammonia-lyase, a B12-dependent enzyme. Evidence for two intermediates in the catalytic process.乙醇胺氨裂解酶（一种依赖维生素B12的酶）的作用机制。催化过程中两个中间体的证据。
J Biol Chem. 1974 Mar 25;249(6):1683-8.
3
The mechanism of action of ethanolamine ammonia-lyase, a B-12-dependent enzyme. The participation of paramagnetic species in the catalytic deamination of 2-aminopropanol.乙醇胺氨裂解酶（一种依赖维生素B12的酶）的作用机制。顺磁物质参与2-氨基丙醇的催化脱氨反应。
J Biol Chem. 1974 Jul 25;249(14):4537-44.
4
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Studies with isopropanolamine, a true substrate.乙醇胺氨裂解酶（一种依赖腺苷钴胺素的酶）的作用机制。以异丙醇胺（一种真正的底物）进行的研究。
J Biol Chem. 1980 Aug 10;255(15):7444-8.
5
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. The source of the third methyl hydrogen in the 5'-deoxyadenosine generated from the cofactor during catalysis.乙醇胺氨裂解酶（一种依赖腺苷钴胺素的酶）的作用机制。催化过程中从辅因子生成的5'-脱氧腺苷中第三个甲基氢的来源。
J Biol Chem. 1976 Jun 25;251(12):3734-7.
6
Coenzyme-B12-dependent enzyme reactions: a spectrophotometric rapid kinetic study of ethanolamine ammonia-lyase.依赖辅酶B12的酶反应：乙醇胺氨裂解酶的分光光度快速动力学研究
FEBS Lett. 1975 May 1;53(2):193-8. doi: 10.1016/0014-5793(75)80018-4.
7
Mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Proton nuclear magnetic resonance studies of the binding of adenine nucleosides and substrate to ethanolamine ammonia-lyase.乙醇胺氨裂解酶的作用机制，一种依赖腺苷钴胺素的酶。腺嘌呤核苷和底物与乙醇胺氨裂解酶结合的质子核磁共振研究。
J Biol Chem. 1975 Oct 25;250(20):8023-9.
8
The substrate-dependent steric course of the ethanolamine ammonia-lyase reaction.乙醇胺氨裂解酶反应的底物依赖性空间进程。
Eur J Biochem. 1980 May;106(1):211-24. doi: 10.1111/j.1432-1033.1980.tb06012.x.
9
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Evidence that the hydrogen transfer mechanism involves a second intermediate hydrogen carrier in addition to the cofactor.乙醇胺氨裂解酶的作用机制，一种依赖腺苷钴胺素的酶。有证据表明，除辅因子外，氢转移机制还涉及第二种中间氢载体。
J Biol Chem. 1985 Dec 25;260(30):16131-6.
10
Interaction between ethanolamine ammonia-lyase and methylcobalamin. Half-site reactivity with an adenosylcobalamin-dependent enzyme.乙醇胺氨裂解酶与甲钴胺的相互作用。与腺苷钴胺素依赖性酶的半位点反应性。
J Biol Chem. 1975 Dec 10;250(23):8997-9001.

引用本文的文献

1
Novel coenzyme B12-dependent interconversion of isovaleryl-CoA and pivalyl-CoA.新型辅酶 B12 依赖的异戊酰辅酶 A 和特戊酰辅酶 A 的互变。
J Biol Chem. 2012 Feb 3;287(6):3723-32. doi: 10.1074/jbc.M111.320051. Epub 2011 Dec 13.
2
Vitamin B(12) and alpha-Ribonucleosides.维生素B12与α-核糖核苷
Tetrahedron. 2008 Jan 1;64(1):9-38. doi: 10.1016/j.tet.2007.08.061.
3
Evidence that a B12-adenosyl transferase is encoded within the ethanolamine operon of Salmonella enterica.有证据表明，一种B12-腺苷转移酶在肠炎沙门氏菌的乙醇胺操纵子内编码。
J Bacteriol. 2004 Nov;186(22):7635-44. doi: 10.1128/JB.186.22.7635-7644.2004.
4
The 17-gene ethanolamine (eut) operon of Salmonella typhimurium encodes five homologues of carboxysome shell proteins.鼠伤寒沙门氏菌的17基因乙醇胺（eut）操纵子编码五个羧基体壳蛋白的同源物。
J Bacteriol. 1999 Sep;181(17):5317-29. doi: 10.1128/JB.181.17.5317-5329.1999.
5
Functions required for vitamin B12-dependent ethanolamine utilization in Salmonella typhimurium.鼠伤寒沙门氏菌中维生素B12依赖性乙醇胺利用所需的功能。
J Bacteriol. 1989 Jun;171(6):3316-23. doi: 10.1128/jb.171.6.3316-3323.1989.
6
The mechanism of cobalamin-dependent rearrangements.钴胺素依赖性重排的机制。
Mol Cell Biochem. 1977 Apr 12;15(2):89-108. doi: 10.1007/BF01793331.