发育和衰老对犬淋巴细胞对植物血凝素反应的影响。
Effect of development and aging on the response of canine lymphocytes to phytohemagglutinin.
作者信息
Gerber J D, Brown A L
出版信息
Infect Immun. 1974 Oct;10(4):695-9. doi: 10.1128/iai.10.4.695-699.1974.
Abstract
The stage of development and age were found to effect the responsiveness of dog T-lymphocytes to phytohemagglutinin. T-lymphocytes from beagles 0 to 4 weeks of age showed significantly less response to phytohemagglutinin (P < 0.001) than T-lymphocytes from these same dogs at 6 to 12 weeks of age. Peak response to phytohemagglutinin occurred between 6 weeks to 6 months of age, after which there was a significant correlation (P < 0.02) between increase in age and decrease in phytohemagglutinin responsiveness.
摘要
研究发现，发育阶段和年龄会影响犬T淋巴细胞对植物血凝素的反应性。0至4周龄比格犬的T淋巴细胞对植物血凝素的反应明显低于这些犬6至12周龄时的T淋巴细胞（P<0.001）。对植物血凝素的峰值反应出现在6周龄至6月龄之间，此后，年龄增长与植物血凝素反应性降低之间存在显著相关性（P<0.02）。
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