Shik L L, Len'kova N A
Biull Eksp Biol Med. 1979 May;87(5):400-2.
The effect of lethal burn injury on the parameters of hemodynamics and respiration was investigated in intact rabbits and those with disconnected aortal and sinocarotid reflexogenic zones. The rabbits of both groups demonstrated similar changes in cardiac output and total oxygen consumption. Unlike intact animals, the burn in rabbits with disconnected reflexogenic zones did not lead to a marked increase in the peripheral vascular resistance. Accordingly, the systemic arterial blood pressure in them fell to a considerably greater extent than that in the intact animals. The life span of the rabbits exposed to burns was less as compared to the intact ones. A reflex compensatory nature of the increased peripheral vascular resistance in burn shock is suggested.
在完整的兔子以及主动脉和窦颈动脉反射源区被切断的兔子身上,研究了致死性烧伤对血流动力学和呼吸参数的影响。两组兔子的心输出量和总耗氧量均呈现出相似的变化。与完整动物不同,反射源区被切断的兔子烧伤后外周血管阻力并未显著增加。因此,它们的体循环动脉血压下降幅度比完整动物大得多。与完整兔子相比,遭受烧伤的兔子寿命更短。提示烧伤休克时外周血管阻力增加具有反射性代偿性质。