Kurbanov Sh K, Alimkhodzhaeva Ch R
Biull Eksp Biol Med. 1979 May;87(5):412-4.
In acute experiments on white male rats the enzyme spectrum of pancreas homogenate was studied in the process of 30-day adaptation after 3-hour exposure to the muscular loading (compulsory swimming in the water at a temperature of 32 +/- 1 degree C), the heat (overheating at 40-41 degrees C) and the cold (cooling at -3-4 degrees C). It was shown that the initial periods of adaptation to the factors mentioned (2d-12th day) were characterized by a considerable decrease in the activity of all the enzymes under study. With subsequent adaptation of the animal body to these stresses the enzyme activity level recovered to the initial value (18-24th day) and remained more or less stable up to the end of the experiment (30th day). It is suggested that the alteration of the pancreatic enzyme spectrum proceeds with the participation of the hypothalamic-hypophyseal-adrenal systems as a general adaptation syndrome.
在对白雄性大鼠进行的急性实验中，研究了胰腺匀浆的酶谱在以下三种情况30天适应过程中的变化：在32±1℃水温下强迫游泳3小时的肌肉负荷、40 - 41℃的过热以及-3 - 4℃的低温。结果表明，对上述因素适应的初始阶段（第2天至第12天），所研究的所有酶的活性均显著下降。随着动物机体随后对这些应激的适应，酶活性水平恢复到初始值（第18天至第24天），并在实验结束（第30天）前或多或少保持稳定。提示胰腺酶谱的改变是在下丘脑 - 垂体 - 肾上腺系统参与下作为一种全身适应综合征进行的。
