西咪替丁对大鼠实验性慢性胃溃疡的作用。
Effect of cimetidine on chronic gastric ulcers produced experimentally in rats.
作者信息
MacPherson B R, Kilam S K
出版信息
Can J Surg. 1979 Jul;22(4):385-7.
PMID:455171
Abstract
The authors have studied the effects of cimetidine on the healing of chronic gastric ulcers induced in rats. Gastric ulcers were produced by topical application of 60% acetic acid to the serosal surface of the lesser curvature of the stomach. Oral administration of cimetidine, 150 mg/kg daily, in two divided doses for a maximum of 14 days failed to produce any significant acceleration of healing.
摘要
作者研究了西咪替丁对大鼠慢性胃溃疡愈合的影响。通过将60%的醋酸局部涂抹于胃小弯的浆膜表面来制造胃溃疡。每天口服西咪替丁150毫克/千克，分两次给药，最长给药14天，未能显著加速溃疡愈合。
相似文献
1
Effect of cimetidine on chronic gastric ulcers produced experimentally in rats.西咪替丁对大鼠实验性慢性胃溃疡的作用。
Can J Surg. 1979 Jul;22(4):385-7.
2
Effects of cimetidine on healing of chronic gastric and duodenal ulcers in dogs.西咪替丁对犬慢性胃溃疡和十二指肠溃疡愈合的影响。
Am J Dig Dis. 1978 Feb;23(2):166-8. doi: 10.1007/BF01073194.
3
Effect of cimetidine on the regeneration of the gastric mucosa around a peptic ulcer.西咪替丁对消化性溃疡周围胃黏膜再生的影响。
Am J Gastroenterol. 1982 May;77(5):331-4.
4
The effect of cimetidine on stress ulcers.西咪替丁对应激性溃疡的作用。
Int Surg. 1978 Mar;63(3):143-6.
5
The effect of gastronomical concentrations of ethanol on therapeutic effect of cimetidine and sucralfate in rats with chronic gastric ulcers.
Pol J Pharmacol Pharm. 1989 May-Jun;41(3):259-62.
6
[Effects of cimetidine on stress ulcers in the rat (author's transl)].西咪替丁对大鼠应激性溃疡的作用（作者译）
J Chir (Paris). 1979 Oct;116(10):605.
7
[Cimetidine in experimental gastric ulcers induced by pyloric ligation].
Boll Soc Ital Biol Sper. 1981 Jan 15;57(1):80-5.
8
Has cimetidine revolutionised the medical treatment of peptic ulceration?西咪替丁是否彻底改变了消化性溃疡的医学治疗方法？
J Hum Nutr. 1979 Oct;33(5):367-70.
9
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat.硫糖铝、兰索拉唑和西咪替丁对磷酸氢化可的松所致大鼠慢性胃溃疡愈合延迟的影响。
Am J Med. 1991 Aug 8;91(2A):15S-19S. doi: 10.1016/0002-9343(91)90446-5.
10
Effects of the novel anti-ulcer agent 1-(5'-oxohexyl)-3-methyl-7-propyl xanthine on experimental ulcers and gastric secretion in rats.新型抗溃疡药物1-(5'-氧代己基)-3-甲基-7-丙基黄嘌呤对大鼠实验性溃疡和胃分泌的影响
Arzneimittelforschung. 1989 Jun;39(6):689-94.
Zotero 插件