Griffin T W, Beaufait D, Blasko J C
Cancer. 1979 Jul;44(1):276-80. doi: 10.1002/1097-0142(197907)44:1<276::aid-cncr2820440147>3.0.co;2-0.
Thirty-nine patients with low grade cystic cerebellar astrocytomas were treated at the University of Washington and Children's Orthopedic Hospital in Seattle, Washington, between 1955 and 1977; 29 were treated with partial or complete resection alone, and 10 received radiation therapy after various types of surgical procedures. With a mean follow-up time of 7 years, the survival rate for patients who had complete resections of their primary disease was 100%. The relapse-free survival rate was 82%. The relapse-free survival rate for patients treated primarily with partial resection alone was 36%. Postoperative irradiation after partial resection for both primary and recurrent disease resulted in a relapse-free survival rate of 83%. If complete tumor excision is not possible, postoperative radiation therapy is recommended following partial resection.
1955年至1977年间,华盛顿大学和华盛顿州西雅图市儿童矫形医院对39例低度囊性小脑星形细胞瘤患者进行了治疗;29例仅接受了部分或完全切除,10例在接受了各种手术治疗后接受了放射治疗。平均随访时间为7年,原发性疾病完全切除患者的生存率为100%。无复发生存率为82%。仅接受部分切除治疗的患者无复发生存率为36%。原发性和复发性疾病部分切除术后的术后放疗导致无复发生存率为83%。如果无法完全切除肿瘤,建议在部分切除术后进行术后放疗。