Mullins J D, Barnes R P
Cancer. 1979 Jul;44(1):315-22. doi: 10.1002/1097-0142(197907)44:1<315::aid-cncr2820440154>3.0.co;2-e.
A bronchial mucoepidermoid tumor in a 13-year-old female was studied by light and electron microscopy. This is the seventh reported case of this rare bronchial neoplasm in a person less than 16 years of age and the only case, in any age group, which has been studied ultrastructurally. All reported cases of bronchial mucoepidermoid tumors in childhood have been histologically of the low grade (well differentiated) variety with a benign clinical course. Although there are histological features which distinguish this lesion from the even rarer bronchial mucous gland adenoma, the clinical features and biological potential of the two lesions in this age group appear to be identical. The optimal surgical therapy for bronchial mucoepidermoid tumors and mucous gland adenomas, when occurring in children, is identical. There must be total removal of either lesion with the sacrifice of as little normal lung as possible. When technically possible, a sleeve resection of the involved bronchus is recommended; however, in most cases, the location of the lesion requires a lobectomy for complete removal.
对一名13岁女性的支气管黏液表皮样瘤进行了光镜和电镜研究。这是第7例报道的16岁以下人群中这种罕见支气管肿瘤的病例，也是任何年龄组中唯一进行过超微结构研究的病例。所有报道的儿童支气管黏液表皮样瘤病例在组织学上均为低级别（高分化）类型，临床病程良性。尽管存在一些组织学特征可将此病变与更为罕见的支气管黏液腺腺瘤区分开来，但这两种病变在该年龄组的临床特征和生物学潜能似乎相同。儿童期发生的支气管黏液表皮样瘤和黏液腺腺瘤的最佳手术治疗方法相同。必须将任何一种病变完全切除，同时尽可能少地牺牲正常肺组织。在技术可行时，建议对受累支气管进行袖状切除术；然而，在大多数情况下，病变的位置需要进行肺叶切除术以完全切除。
