苏拉明增强环磷酰胺或阿霉素对肌肉注射接种的艾氏癌的化疗作用。
Suramin enhancement of the chemotherapeutic actions of cyclophosphamide or adriamycin of intramuscularly-implanted Ehrlich carcinoma.
作者信息
Osswald H, Youssef M
出版信息
Cancer Lett. 1979 May;6(6):337-43. doi: 10.1016/s0304-3835(79)80091-9.
PMID:455271
Abstract
The chemotherapeutic action of cyclophosphamide or adriamycin monotherapy on hyperdiploid Ehrlich carcinoma was compared with that of sequential combinations of suramin and cyclophosphamide and suramin and adriamycin. The chemotherapeutic action of the suramin-cyclophosphamide combination or of the adriamycin-surmin combination was significantly enhanced when the combination partners were applied at definite intervals.
摘要
将环磷酰胺或阿霉素单药治疗对超二倍体艾氏癌的化疗作用，与苏拉明和环磷酰胺以及苏拉明和阿霉素的序贯联合治疗的化疗作用进行了比较。当联合用药的两种药物按一定间隔给药时，苏拉明 - 环磷酰胺联合用药或阿霉素 - 苏拉明联合用药的化疗作用显著增强。
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