顺二氯二氨铂（II）治疗IVB期霍奇金病的II期研究。
Phase II study of cis-dischlorodiammineplatinum(II) in stage IVB Hodgkin's disease.
作者信息
Corder M P, Elliott T E, Maguire L C, Leimert J T, Panther S K, Lachenbruch P A
出版信息
Cancer Treat Rep. 1979 May;63(5):763-6.
PMID:455312
Abstract
A broad phase II study of cis-dichlorodiammineplatinum(II) was conducted. Eight patients with stage IVB Hodgkin's disease were studied. Four of these patients attained an objective partial remission of 7--19+ weeks' duration. The usual time to the occurrence of a greater than 25% response was 1 week. This drug is active in far-advanced Hodgkin's disease with a projected lower limit of response rate from 19% to 21%.
摘要
开展了一项关于顺二氯二氨铂（II）的广泛II期研究。对8例IVB期霍奇金病患者进行了研究。其中4例患者实现了持续7 - 19 +周的客观部分缓解。出现大于25%缓解的通常时间为1周。该药物在晚期霍奇金病中具有活性，预计缓解率下限为19%至21%。
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