Shubik P
Proc Natl Acad Sci U S A. 1972 Apr;69(4):1052-5. doi: 10.1073/pnas.69.4.1052.
The prevention of cancer by the elimination of, or decreased contact with, chemical carcinogens is dealt with under three headings. (a) Exposure of special groups: occupational cancer, iatronic cancer; (b) exposure of whole populations; (c) discovery of chemical carcinogens in the course of toxicity studies. It is most important that a major effort be made to interrelate findings in man with those in the laboratory. Combination and organization of the findings from many approaches: clinical and preventive medicine, public health, environmental protection, and laboratory research are required.
通过消除化学致癌物或减少与化学致癌物的接触来预防癌症,可分为以下三个方面进行探讨。(a) 特殊人群的暴露:职业性癌症、医源性癌症;(b) 全体人群的暴露;(c) 在毒性研究过程中发现化学致癌物。最重要的是要做出重大努力,将人体研究结果与实验室研究结果相互联系起来。需要综合和整理来自多种途径的研究结果:临床与预防医学、公共卫生、环境保护以及实验室研究。