学龄儿童对风疹活疫苗（森德希尔株）的抗体反应。
Antibody response in school children to live rubella vaccine (Cendehill strain).
作者信息
Iwakata S, Elkerton L E, Rhodes A J, Bull J A, Labzoffsky N A
出版信息
Can Med Assoc J. 1972 May 6;106(9):980-2.
The efficacy of an attenuated rubella virus vaccine, Cendevax, was tested on 65 school children. Forty-nine of them (75%) had pre-existing antibodies and in these there was no increase in the HAI antibody titres after administration of the vaccine. Sixteen children (25%) had no demonstrable rubella HAI antibody prior to vaccination. From the latter group, postvaccination serum samples were available from only 11, and 10 of these seronegative children showed seroconversion after vaccination. The geometric mean HAI titre was 1:180. Seven of the 10 postvaccination serum samples had complement-fixing antibodies and specific IgM antibodies were detected by the immunofluorescence test in 8. No correlation was observed between the CF and the IgM antibodies.
对65名学童测试了减毒风疹病毒疫苗Cendevax的疗效。其中49名（75%）此前已有抗体，接种疫苗后这些儿童的血凝抑制（HAI）抗体效价没有升高。16名儿童（25%）在接种疫苗前没有可检测到的风疹HAI抗体。在后一组中，仅11名儿童有接种疫苗后的血清样本，其中10名血清阴性儿童在接种疫苗后出现了血清转化。几何平均HAI效价为1:180。10份接种疫苗后的血清样本中有7份有补体结合抗体，8份通过免疫荧光试验检测到特异性IgM抗体。未观察到补体结合抗体和IgM抗体之间的相关性。
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