Iwakata S, Rhodes A J, Labzoffsky N A
Can Med Assoc J. 1972 Feb 19;106(4):327-30.
The applicability of the immunofluorescence (IF) test to the diagnosis of primary rubella infection was investigated. The test is based on the detection of rubella-specific antibodies in the IgM fraction of immunoglobulins. The results indicate the usefulness of the IF test for the diagnosis of primary rubella infection on a single serum specimen collected at a proper time. The test is also of value in the differentiation of primary infection from reinfection, since in reinfection no rubella-specific antibodies are found in the IgM fraction. The test is also valuable for the detection of fetal infection in utero since the persistence of IgM antibodies in pregnant women is indicative of fetal infection.
研究了免疫荧光(IF)试验在原发性风疹感染诊断中的适用性。该试验基于检测免疫球蛋白IgM部分中的风疹特异性抗体。结果表明,IF试验对于在适当时间采集的单一血清标本诊断原发性风疹感染是有用的。该试验在区分原发性感染和再感染方面也有价值,因为在再感染时,IgM部分中未发现风疹特异性抗体。该试验对于检测子宫内胎儿感染也很有价值,因为孕妇体内IgM抗体的持续存在表明胎儿感染。