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Methotrexate nephrotoxicity.

作者信息

Fox R M

机构信息

Ludwig Institute for Cancer Research, University of Sydney, New South Wales, Australia.

出版信息

Clin Exp Pharmacol Physiol Suppl. 1979;5:43-5.

PMID:45558
Abstract

The use of high dose methotrexate therapy in the treatment of malignant disease has been complicated by nephrotoxicity. Analysis of the basic physico-chemical properties of methotrexate has allowed the development of improved techniques of administering methotrexate, at high dose, which greatly reduces the incidence of nephrotoxicity.

摘要

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