Baća I, Bieger W, Mittmann U, Saggau W, Schmidt-Gayk H, Storch H H
Chir Forum Exp Klin Forsch. 1979:49-53. doi: 10.1203/00006450-198601000-000233.
The effects of pulsatile and nonpulsatile flow pattern on pancreas and liver blood flow were studied in nine dogs on cardiopulmonary bypass (CPB). Furthermore, plasma levels of glucose, insulin, glucagon, growth hormone, and cholinesterase were compared in 20 patients subjected to open heart surgery with either pulsatile or nonpulsatile perfusion. Impairment of liver and pancreas function was significantly greater at the end of CPB and 48 h afterwards with nonpulsatile flow as compared with the pulsatile flow pattern. A decrease of intestinal blood flow that was demonstrated in dogs subjected to nonpulsatile perfusion could at least in part be responsible for the difference in postoperative organ function observed in patients after CPB.
在九只接受体外循环（CPB）的犬中，研究了搏动性和非搏动性血流模式对胰腺和肝脏血流的影响。此外，对20例接受心脏直视手术并采用搏动性或非搏动性灌注的患者的血浆葡萄糖、胰岛素、胰高血糖素、生长激素和胆碱酯酶水平进行了比较。与搏动性血流模式相比，非搏动性血流在CPB结束时及之后48小时对肝脏和胰腺功能的损害明显更大。在接受非搏动性灌注的犬中观察到的肠血流量减少至少部分可解释CPB术后患者器官功能的差异。
