Halon D A, Amitai N, Gotsman M S, Lewis B S
Eur J Cardiol. 1979 May;9(5):393-404.
Echocardiography was performed in 13 normal neonates on the first day of life and repeated after 1 wk, 1 mth and 3 mth. Measurements were made of cardiac chamber size and wall thickness, mitral, tricuspid and pulmonary valve motion, right and left ventricular systolic time intervals, and of fractional left ventricular shortening (%deltaS) and mean velocity of circumferential fibre shortening (mean Vcf). During the study there was a relative decrease in right ventricular cavity size and wall thickness with an increase in the pulmonary valve EF slope, indicating a fall in pulmonary artery pressure with regression of the right ventricle. Left ventricular size and thickness increased while LVET became longer, possibly the consequence of an increasing left ventricular afterload. There was not a significant change in %deltaS and mean Vcf during the study period. The greatest change from right to left ventricular preponderance occurred between 1 wk and 1 mth of life and was accompanied by changes in the mean frontal QRS axis of the electrocardiogram. The study shows that significant changes occur in the echocardiogram during the first 3 mth of life; neonatal echocardiograms should be interpreted not only in relation to the baby's weight, but also to its age.
对13名正常新生儿在出生第一天进行了超声心动图检查，并在1周、1个月和3个月后重复检查。测量了心腔大小、室壁厚度、二尖瓣、三尖瓣和肺动脉瓣运动、左右心室收缩时间间期，以及左心室缩短分数（%deltaS）和圆周纤维缩短平均速度（平均Vcf）。在研究过程中，右心室腔大小和室壁厚度相对减小，肺动脉瓣EF斜率增加，表明随着右心室的消退肺动脉压力下降。左心室大小和厚度增加，而左心室射血时间（LVET）变长，这可能是左心室后负荷增加的结果。在研究期间，%deltaS和平均Vcf没有显著变化。从右心室优势到左心室优势的最大变化发生在出生后1周和1个月之间，并伴有心电图平均额面QRS电轴的变化。该研究表明，在出生后的前3个月内超声心动图会发生显著变化；新生儿超声心动图的解读不仅应与婴儿体重相关，还应与年龄相关。
