肝细胞分泌蛋白质受到蛋白酶抑制剂N-α-甲苯磺酰-L-赖氨酰氯甲烷的抑制，但不受糖基化抑制剂衣霉素的抑制。 - Suppr

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超能文献

Secretion of proteins from liver cells is suppressed by the proteinase inhibitor N-alpha-tosyl-L-lysyl chloromethane, but not by tunicamycin, an inhibitor of glycosylation.

作者信息

Edwards K, Nagashima M, Dryburgh H, Wykes A, Schreiber G

出版信息

FEBS Lett. 1979 Apr 15;100(2):269-72. doi: 10.1016/0014-5793(79)80349-x.

DOI:10.1016/0014-5793(79)80349-x

PMID:456565

Abstract

摘要

相似文献

Secretion of proteins from liver cells is suppressed by the proteinase inhibitor N-alpha-tosyl-L-lysyl chloromethane, but not by tunicamycin, an inhibitor of glycosylation.肝细胞分泌蛋白质受到蛋白酶抑制剂N-α-甲苯磺酰-L-赖氨酰氯甲烷的抑制，但不受糖基化抑制剂衣霉素的抑制。

FEBS Lett. 1979 Apr 15;100(2):269-72. doi: 10.1016/0014-5793(79)80349-x.

Tosyl-lysyl chloromethane alters glucocorticoid-receptor complex nuclear binding and physical properties.

Endocrinology. 1984 Jul;115(1):65-72. doi: 10.1210/endo-115-1-65.

N-alpha-Tosyl-L-lysine chloromethyl ketone and N-alpha-tosyl-L-phenylalanine chloromethyl ketone inhibit protein kinase C.N-α-对甲苯磺酰-L-赖氨酸氯甲基酮和N-α-对甲苯磺酰-L-苯丙氨酸氯甲基酮可抑制蛋白激酶C。

FEBS Lett. 1985 Oct 14;190(2):342-4. doi: 10.1016/0014-5793(85)81315-6.

Inhibition of the transformation-specific kinase in ASV-transformed cells by N-alpha-tosyl-L-lysyl chloromethyl ketone.

Cell. 1979 Oct;18(2):369-74. doi: 10.1016/0092-8674(79)90056-4.

Differential inhibition of globin chain synthesis by tosyl-L-lysyl chloromethyl ketone.甲苯磺酰-L-赖氨酰氯甲基酮对珠蛋白链合成的差异性抑制作用。

Life Sci. 1981 Nov 2;29(18):1873-9. doi: 10.1016/0024-3205(81)90518-x.

Effects of N alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes.Nα-对甲苯磺酰-L-赖氨酰氯甲基酮对细胞毒性T淋巴细胞活性的影响。

J Immunol. 1980 Mar;124(3):1028-33.

Evidence for an active-center cysteine in the SH-proteinase alpha-clostripain through use of N-tosyl-L-lysine chloromethyl ketone.通过使用N-对甲苯磺酰-L-赖氨酸氯甲基酮证明SH蛋白酶α-梭菌蛋白酶中存在活性中心半胱氨酸。

FEBS Lett. 1984 Jul 23;173(1):58-62. doi: 10.1016/0014-5793(84)81017-0.

Inhibition of initiation of protein synthesis by tosyl-L-lysyl chloromethyl ketone.

Can J Biochem. 1981 May;59(5):321-7. doi: 10.1139/o81-045.

Inactivation of cyclic GMP-dependent protein kinase by N alpha-tosyl-L-lysine chloromethylketone.Nα-对甲苯磺酰-L-赖氨酸氯甲基酮对环磷酸鸟苷依赖性蛋白激酶的失活作用。

Life Sci. 1981 Sep 21;29(12):1235-41. doi: 10.1016/0024-3205(81)90228-9.

The site of action of N-alpha-tosyl-L-lysyl-chloromethyl-ketone (TLCK) on cloned cytotoxic T lymphocytes.N-α-对甲苯磺酰-L-赖氨酰氯甲基酮（TLCK）对克隆化细胞毒性T淋巴细胞的作用位点

J Immunol. 1983 Nov;131(5):2477-83.

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Specificity and inhibition of glucocorticoid-induced macrocortin secretion from rat peritoneal macrophages.糖皮质激素诱导大鼠腹腔巨噬细胞分泌巨皮质素的特异性及抑制作用

Br J Pharmacol. 1983 Jun;79(2):587-94. doi: 10.1111/j.1476-5381.1983.tb11033.x.

Biosynthesis and regulation of rat alpha 1-inhibitor3, a negative acute-phase reactant of the macroglobulin family.大鼠α1-抑制剂3的生物合成与调控，一种巨球蛋白家族的负急性期反应物。

Biochem J. 1987 Jul 15;245(2):493-500. doi: 10.1042/bj2450493.

Castanospermine inhibits glucosidase I and glycoprotein secretion in human hepatoma cells.栗精胺抑制人肝癌细胞中的葡糖苷酶I和糖蛋白分泌。

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