Hughes G R, Whaley K
Br Med J. 1972 Dec 2;4(5839):533-6. doi: 10.1136/bmj.4.5839.533.
Sjögren's syndrome is a common accompaniment of rheumatoid arthritis and other connective-tissue diseases as well as several diseases thought to have an immunological basis. Despite the wide spectrum of clinical features and serological abnormalities the condition is, if anything, underdiagnosed. A clinical subgroup of patients with Sjögren's syndrome can be distinguished by their pronounced hypergammaglobulinaemia, widespread and prominent immunological abnormalities, severe salivary gland swelling, and mild or absent arthritis. It is in this group that lymphoma development has been a complication.
干燥综合征是类风湿关节炎和其他结缔组织疾病以及一些被认为具有免疫基础的疾病的常见伴随病症。尽管其临床特征和血清学异常表现多样，但该病实际上存在诊断不足的情况。干燥综合征患者的一个临床亚组可通过其显著的高球蛋白血症、广泛且突出的免疫异常、严重的唾液腺肿大以及轻微或无关节炎来区分。正是在这一亚组患者中，淋巴瘤已成为一种并发症。
