Gaevyĭ M D, Mal'tsev V G, Pogorelyĭ V E
Fiziol Zh SSSR Im I M Sechenova. 1979 Feb;65(2):263-8.
Autoregulation of cerebral blood flow (ACBF) under orthostatic tests (OT) was estimated in acute experiments on rabbits and cats under local anesthesia according to changes of perfusion pressure (PP) in carotid arteries, cerebral blood flow, pressure in the venous system of the brain, and resistance of cerebral vessels. OT was modeled by turning a special table with animal fixed stop of it from horizontal position to head up or down position for 40--80 degrees. In most experiments ACBF correlated with the changes of PP. Different variations of ACBF and its possible mechanisms are discussed.
在局部麻醉下对兔和猫进行的急性实验中,根据颈动脉灌注压(PP)、脑血流量、脑静脉系统压力和脑血管阻力的变化,评估了体位试验(OT)下的脑血流量自动调节(ACBF)。通过将固定有动物的特殊桌子从水平位置旋转至头朝上或朝下40-80度来模拟OT。在大多数实验中,ACBF与PP的变化相关。讨论了ACBF的不同变化及其可能的机制。