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[人类和动物血脑屏障超微结构组织的若干细节]

[Several details of the ultrastructural organization of the blood-brain barrier in humans and animals].

作者信息

Otellin V A, Rybakov V L, Baikovskaia M N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1979 Mar;65(3):372-8.

PMID:456655
Abstract

Electron microscope study of capillaries, arterioles, and venules of the cerebral cortex, strio--pallidar and nonneurosecretory complexes of hypothalamus of the man, cat, and rat revealed some details of the structure of the basal membrane and its interrelationship with adjacent astrocyte processes. Specific tight--junction type was present constantly among the adjacent membranes of glial cells. The system of the specializations and basal membrane seems to exert regulatory influence upon functioning of the blood--brain barrier.

摘要

对人、猫和大鼠大脑皮层的毛细血管、小动脉和小静脉,以及下丘脑的纹状体苍白球和非神经分泌复合体进行电子显微镜研究,揭示了基底膜结构的一些细节及其与相邻星形胶质细胞突起的相互关系。在神经胶质细胞相邻膜之间始终存在特定类型的紧密连接。特化系统和基底膜似乎对血脑屏障的功能发挥调节作用。

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