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Inhibition of sterol and fatty acid biosyntheses by cerulenin in cell-free systems of yeast.

作者信息

Nomura S, Horiuchi T, Hata T, Omura S

出版信息

J Antibiot (Tokyo). 1972 Jun;25(6):365-8. doi: 10.7164/antibiotics.25.365.

DOI:10.7164/antibiotics.25.365
PMID:4568013
Abstract
摘要

相似文献

1
Inhibition of sterol and fatty acid biosyntheses by cerulenin in cell-free systems of yeast.
J Antibiot (Tokyo). 1972 Jun;25(6):365-8. doi: 10.7164/antibiotics.25.365.
2
The action mechanism of cerulenin. I. Effect of cerulenin on sterol and fatty acid biosynthesis in yeast.浅蓝菌素的作用机制。I. 浅蓝菌素对酵母中甾醇和脂肪酸生物合成的影响。
J Biochem. 1972 May;71(5):783-96. doi: 10.1093/oxfordjournals.jbchem.a129827.
3
[Effect of nystatin and levorin on the biosynthesis of sterols and fatty acids in cell-free extracts of Saccharomyces cerevisiae].
Antibiotiki. 1971 Mar;16(3):279-82.
4
Target of inhibition by the anti-lipogenic antibiotic cerulenin of sterol synthesis in yeast.抗脂肪生成抗生素浅蓝菌素在酵母中对甾醇合成的抑制靶点。
Biochem Biophys Res Commun. 1974 Apr 23;57(4):1119-24. doi: 10.1016/0006-291x(74)90812-2.
5
Structural specificity of bile acid for inhibition of sterol synthesis in cell-free extracts of yeast.胆汁酸对酵母无细胞提取物中甾醇合成抑制作用的结构特异性
Biochim Biophys Acta. 1972 Jul 7;270(3):397-406.
6
Reversal of cerulenin-induced inhibition of phospholipids and sterol synthesis by exogenous fatty acids/sterols in Epidermophyton floccosum.外源性脂肪酸/固醇对絮状表皮癣菌中铜绿假单胞菌素诱导的磷脂和固醇合成抑制的逆转作用
Biochim Biophys Acta. 1987 Sep 25;921(2):341-6. doi: 10.1016/0005-2760(87)90035-x.
7
Inhibition of ergosterol biosynthesis is not accompanied by a change in fatty acid composition in Saccharomyces cerevisiae treated with the antifungal agent 6-amino-2-n-pentylthiobenzothiazole.用抗真菌剂6-氨基-2-正戊基硫代苯并噻唑处理酿酒酵母时,麦角固醇生物合成的抑制并未伴随着脂肪酸组成的变化。
FEMS Microbiol Lett. 1997 May 1;150(1):43-7. doi: 10.1111/j.1574-6968.1997.tb10347.x.
8
Prevention of cyclic and triton-induced increases in hydroxymethylglutaryl coenzyme A reductase and sterol synthesis by puromycin.嘌呤霉素对环磷酰胺和曲通诱导的羟甲基戊二酰辅酶A还原酶及甾醇合成增加的预防作用
J Biol Chem. 1969 May 10;244(9):2299-305.
9
Cerulenin.浅蓝菌素
Methods Enzymol. 1981;72:520-32.
10
Substitution of cellular fatty acids in yeast cells by the antibiotic cerulenin and exogenous fatty acids.抗生素浅蓝菌素和外源脂肪酸对酵母细胞中细胞脂肪酸的替代作用。
Biochim Biophys Acta. 1975 Dec 17;409(3):267-73. doi: 10.1016/0005-2760(75)90022-3.

引用本文的文献

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Chemical Exchanges between Multilateral Symbionts.多边共生体之间的化学交换。
Org Lett. 2021 Mar 5;23(5):1648-1652. doi: 10.1021/acs.orglett.1c00068. Epub 2021 Feb 16.
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Cerulenin blockade of fatty acid synthase reverses hepatic steatosis in ob/ob mice.塞利霉素阻断脂肪酸合酶可逆转 ob/ob 小鼠的肝脂肪变性。
PLoS One. 2013 Sep 27;8(9):e75980. doi: 10.1371/journal.pone.0075980. eCollection 2013.
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Palmitoyl acyltransferase assays and inhibitors (Review).棕榈酰转移酶测定与抑制剂(综述)
Mol Membr Biol. 2009 Jan;26(1):5-13. doi: 10.1080/09687680802683839. Epub 2009 Jan 16.
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Inhibition of the fungal fatty acid synthase type I multienzyme complex.对真菌I型脂肪酸合酶多酶复合体的抑制作用。
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12803-8. doi: 10.1073/pnas.0805827105. Epub 2008 Aug 25.
5
Relationship between the structures of fatty acid amide derivatives and their antimicrobial activities.脂肪酸酰胺衍生物的结构与其抗菌活性之间的关系。
Antimicrob Agents Chemother. 1974 Aug;6(2):207-15. doi: 10.1128/AAC.6.2.207.
6
Enzymes of secondary metabolism and the biosynthesis of macrolide antibiotics.次生代谢酶与大环内酯类抗生素的生物合成
Folia Microbiol (Praha). 1986;31(5):402-21. doi: 10.1007/BF02936606.
7
Inhibition of de novo fatty acid synthesis by the antibiotic cerulenin in Bacillus subtilis: effects on citrate-Mg2+ transport and synthesis of macromolecules.抗生素浅蓝菌素对枯草芽孢杆菌从头脂肪酸合成的抑制作用:对柠檬酸-Mg2+转运及大分子合成的影响。
Antimicrob Agents Chemother. 1975 Sep;8(3):231-7. doi: 10.1128/AAC.8.3.231.
8
The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis.抗生素浅蓝菌素,作为一种脂肪酸合成抑制剂,是生物化学领域的一种新型工具。
Bacteriol Rev. 1976 Sep;40(3):681-97. doi: 10.1128/br.40.3.681-697.1976.
9
Membranes of Rhodopseudomonas sphaeroides: effect of cerulenin on assembly of chromatophore membrane.球形红假单胞菌的膜:浅蓝菌素对载色体膜组装的影响
J Bacteriol. 1979 Jun;138(3):788-98. doi: 10.1128/jb.138.3.788-798.1979.