大麻与酒精：对模拟驾驶的影响

Cannabis and alcohol: effects on stimulated car driving.

作者信息

Rafaelsen O J, Bech P, Christiansen J, Christrup H, Nyboe J, Rafaelsen L

出版信息

Science. 1973 Mar 2;179(4076):920-3. doi: 10.1126/science.179.4076.920.

DOI:10.1126/science.179.4076.920

Abstract

The effects of cannabis and alcohol on simulated car driving were studied. Cannabis resin containing 4 percent Delta(1)-tetrahydrocannabinol was administered orally in three doses equivalent to 8, 12, and 16 milligrams of that component. Alcohol was given orally in one standard dose of 70 grams. Both cannabis and alcohol increased the time required to brake and start, whereas alcohol increased while cannabis decreased the number of gear changes. An effect of dosage on response was observed with cannabis.

摘要

研究了大麻和酒精对模拟驾驶的影响。口服含有4% Δ(1)-四氢大麻酚的大麻树脂，分三种剂量，分别相当于该成分8毫克、12毫克和16毫克。口服酒精，标准剂量为70克。大麻和酒精都增加了制动和启动所需的时间，而酒精增加了换挡次数，大麻则减少了换挡次数。观察到了大麻剂量对反应的影响。