Ahmad G, Zamenhof S
Growth. 1979 Mar;43(1):58-61.
It has been suggested that in the embryo hormonal steroids may act also as control factors for the growth of neural systems. In the present work progesterone was introduced onto the chorioallantoic membrane of the chick embryo on day 7 or days 7 and 10 of incubation. The embryo, dissected at day 10, showed significant increases in body weight and cerebral hemispheres weight. The response at day 13 was less pronounced; male embryos responded to progesterone more than the female embryos. Progesterone is a precursor to other corticosteroids, but corticosterone itself had a significant harmful effect on embryonal growth. Several possible explanations of these results have been offered. It appears that progesterone itself promotes the growth of the early embryo, but the effect depends on its age and sex.
有人提出，在胚胎中，激素类固醇也可能作为神经系统生长的控制因子。在本研究中，在孵化第7天或第7天和第10天将孕酮引入鸡胚的绒毛尿囊膜。在第10天解剖的胚胎显示体重和大脑半球重量显著增加。第13天的反应不那么明显；雄性胚胎对孕酮的反应比雌性胚胎更明显。孕酮是其他皮质类固醇的前体，但皮质酮本身对胚胎生长有显著的有害影响。对这些结果提出了几种可能的解释。似乎孕酮本身促进早期胚胎的生长，但这种作用取决于胚胎的年龄和性别。
