Leven B
Fortschr Med. 1979 Jun 28;97(24):1119-22.
In acute idiopathic polyneuritis, the slowing of nerve conduction velocity does not allow prognostical statements. However, a marked reduction of muscle potential amplitude after stimulation and recording points implies a large number of damaged axons. This effect occurs earlier and is more reliable than pathological spontaneous activity in the EMG. Following complete or almost complete loss of indirect muscle excitability, improvement of function can be expected only after sprouting of nerve fibers--therefore after some months at best; permanent defects must bei anticipated especially in distal muscle groups. We experienced this most commonly--but not exclusively--in cases with highly acute courses which led to tetraparalytic syndroms. Clinical courses with slowly progressive disease during months and recurrent courses of idiopathic polyneuritis can also lead to permanent paresis.
在急性特发性多神经炎中，神经传导速度减慢无法用于预后判断。然而，刺激和记录点后肌肉电位幅度显著降低意味着大量轴突受损。这种效应比肌电图中的病理性自发活动出现得更早且更可靠。在间接肌肉兴奋性完全或几乎完全丧失后，只有在神经纤维发芽后（因此最快也要几个月后）才有望功能改善；必须预计会出现永久性缺陷，尤其是在远端肌肉群。我们在导致四肢麻痹综合征的高度急性病程的病例中最常（但并非唯一）遇到这种情况。数月来缓慢进展性疾病以及特发性多神经炎的复发病程的临床过程也可导致永久性麻痹。
