Rothman S W, Corwin L M
Infect Immun. 1972 Jan;5(1):103-6. doi: 10.1128/iai.5.1.103-106.1972.
An Escherichia coli-Shigella flexneri hybrid strain which produces an abortive, nonfatal experimental dysentery has inherited relaxed control of ribonucleic acid synthesis from its E. coli parent. This property, coupled with a partial methionine requirement, has been used to explain its long lag phase in vitro, relative to its Shigella parent. It was suggested that such characteristics may contribute to the hybrid's poor survival in the gut resulting in the abortive infection.
一种产生流产型、非致死性实验性痢疾的大肠杆菌-福氏志贺氏菌杂交菌株从其大肠杆菌亲本那里继承了对核糖核酸合成的松弛控制。相对于其志贺氏菌亲本，这一特性与对甲硫氨酸的部分需求一起，被用来解释其在体外较长的迟缓期。有人提出，这些特征可能导致该杂交菌株在肠道中存活不佳，从而引发流产型感染。
