影响福氏志贺氏菌毒力的因素：核糖核酸合成调控松弛的菌株。
Factors affecting virulence of Shigella flexneri: strain with relaxed control of ribonucleic acid synthesis.
作者信息
Rothman S W, Corwin L M
出版信息
Infect Immun. 1972 Jan;5(1):103-6. doi: 10.1128/iai.5.1.103-106.1972.
Abstract
An Escherichia coli-Shigella flexneri hybrid strain which produces an abortive, nonfatal experimental dysentery has inherited relaxed control of ribonucleic acid synthesis from its E. coli parent. This property, coupled with a partial methionine requirement, has been used to explain its long lag phase in vitro, relative to its Shigella parent. It was suggested that such characteristics may contribute to the hybrid's poor survival in the gut resulting in the abortive infection.
摘要
一种产生流产型、非致死性实验性痢疾的大肠杆菌-福氏志贺氏菌杂交菌株从其大肠杆菌亲本那里继承了对核糖核酸合成的松弛控制。相对于其志贺氏菌亲本，这一特性与对甲硫氨酸的部分需求一起，被用来解释其在体外较长的迟缓期。有人提出，这些特征可能导致该杂交菌株在肠道中存活不佳，从而引发流产型感染。
相似文献
1
Factors affecting virulence of Shigella flexneri: strain with relaxed control of ribonucleic acid synthesis.影响福氏志贺氏菌毒力的因素：核糖核酸合成调控松弛的菌株。
Infect Immun. 1972 Jan;5(1):103-6. doi: 10.1128/iai.5.1.103-106.1972.
2
Factors affecting virulence of Shigella flexneri: defective methionine synthesis in an Escherichia coli-Shigella hybrid.影响福氏志贺氏菌毒力的因素：大肠杆菌-志贺氏菌杂交体中甲硫氨酸合成缺陷
J Bacteriol. 1972 Oct;112(1):176-82. doi: 10.1128/jb.112.1.176-182.1972.
3
ABORTIVE INTESTINAL INFECTION WITH AN ESCHERICHIA COLI-SHIGELLA FLEXNERI HYBRID STRAIN.由大肠埃希菌-福氏志贺菌杂交菌株引起的顿挫型肠道感染
J Bacteriol. 1965 May;89(5):1374-82. doi: 10.1128/jb.89.5.1374-1382.1965.
4
Studies on the energetic metabolism of Shigella flexneri x Escherichia coli hybrids devoid of penetration ability. IV. Growth characteristics in the presence of some tricarboxylic acid cycle intermediates.对缺乏穿透能力的弗氏志贺菌与大肠杆菌杂交体能量代谢的研究。IV. 某些三羧酸循环中间产物存在时的生长特性。
Zentralbl Bakteriol Orig A. 1976 Oct;236(1):99-104.
5
Stimulation of unbalanced ribonucleic acid synthesis in Escherichia coli by methanol.甲醇对大肠杆菌中不平衡核糖核酸合成的刺激作用。
J Bacteriol. 1972 Apr;110(1):179-85. doi: 10.1128/jb.110.1.179-185.1972.
6
Virulence of Shigella flexneri hybrids expressing Escherichia coli somatic antigens.表达大肠杆菌菌体抗原的福氏志贺菌杂交株的毒力
Infect Immun. 1972 Aug;6(2):104-11. doi: 10.1128/iai.6.2.104-111.1972.
7
[Biochemical and genetic characteristics of enteropathogenic Escherichia coli and Shigella. V. The biological properties of auxotrophic mutants of Shigella flexneri 2a and of Escherichia coli serogroup 0124:K72].[致病性大肠杆菌和志贺氏菌的生化及遗传特征。V. 福氏志贺氏菌2a和大肠杆菌血清群O124:K72营养缺陷型突变体的生物学特性]
Zh Mikrobiol Epidemiol Immunobiol. 1975 Oct(10):130-1.
8
Mechanisms and genetics of resistance to sodium lauryl sulfate in strains of Shigella and Escherichia coli.志贺氏菌和大肠杆菌菌株对十二烷基硫酸钠耐药性的机制与遗传学
Infect Immun. 1971 Sep;4(3):287-94. doi: 10.1128/iai.4.3.287-294.1971.
9
Characterization of mutants of Escherichia coli temperature-sensitive for ribonucleic acid regulation: an unusual phenotype associated with a phenylalanyl transfer ribonucleic acid synthetase mutant.对核糖核酸调节温度敏感的大肠杆菌突变体的特性研究：与苯丙氨酰转移核糖核酸合成酶突变体相关的一种异常表型。
J Bacteriol. 1971 Nov;108(2):627-38. doi: 10.1128/jb.108.2.627-638.1971.
10
On the metabolic characteristics of Shigella flexneri X Escherichia coli, devoid of ability for intracellular multiplication in epithelial cells. III. Oxygen uptake and dehydrogenase activity.
Zentralbl Bakteriol Orig A. 1977 Nov;239(3):352-60.
引用本文的文献
1
Factors affecting virulence of Shigella flexneri: defective methionine synthesis in an Escherichia coli-Shigella hybrid.影响福氏志贺氏菌毒力的因素：大肠杆菌-志贺氏菌杂交体中甲硫氨酸合成缺陷
J Bacteriol. 1972 Oct;112(1):176-82. doi: 10.1128/jb.112.1.176-182.1972.
本文引用的文献
1
EPITHELIAL CELL PENETRATION AS AN ESSENTIAL STEP IN THE PATHOGENESIS OF BACILLARY DYSENTERY.上皮细胞穿透是细菌性痢疾发病机制中的关键步骤。
J Bacteriol. 1964 Nov;88(5):1503-18. doi: 10.1128/jb.88.5.1503-1518.1964.
2
ABORTIVE INTESTINAL INFECTION WITH AN ESCHERICHIA COLI-SHIGELLA FLEXNERI HYBRID STRAIN.由大肠埃希菌-福氏志贺菌杂交菌株引起的顿挫型肠道感染
J Bacteriol. 1965 May;89(5):1374-82. doi: 10.1128/jb.89.5.1374-1382.1965.
3
VIRULENCE OF ESCHERICHIA-SHIGELLA GENETIC HYBRIDS FOR THE GUINEA PIG.埃希氏菌-志贺氏菌基因杂种对豚鼠的毒力
J Bacteriol. 1963 Dec;86(6):1251-8. doi: 10.1128/jb.86.6.1251-1258.1963.
4
A functional analysis of the rel gene in Escherichia coli.大肠杆菌中rel基因的功能分析。
J Mol Biol. 1969 Oct 28;45(2):195-203. doi: 10.1016/0022-2836(69)90099-0.
5
Studies of the impaired inducibility in relaxed mutants of Escherichia coli.大肠杆菌松弛突变体诱导性受损的研究。
Biochim Biophys Acta. 1969 Oct 22;190(2):442-53. doi: 10.1016/0005-2787(69)90093-8.
6
Physiology and genetics of the "ribonucleic acid control" locus in escherichia coli.大肠杆菌中“核糖核酸控制”位点的生理学与遗传学
Bacteriol Rev. 1968 Sep;32(3):206-26. doi: 10.1128/br.32.3.206-226.1968.
Zotero 插件