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酶电极

Enzyme electrodes.

作者信息

Gough D A, Andrade J D

出版信息

Science. 1973 Apr 27;180(4084):380-4. doi: 10.1126/science.180.4084.380.

Abstract

From the discussion of electrodes and enzymes herein, and from the accounts of enzyme electrodes that have appeared in the literature, clinical determinations of certain metabolites and soluble enzymes by means of enzyme electrodes seem quite feasible. Such devices may be made highly specific by the use of appropriate enzymes and a high degree of accuracy can be obtained. Instantaneous and continuous determinations can be made from physiological fluids, and undesirable physiologic responses can theoretically be minimized, thus making long-term clinical monitoring a possibility. Enzyme electrodes may also have a useful lifetime and meet other practical requirements.

摘要

从本文对电极和酶的讨论,以及文献中出现的酶电极的描述来看,通过酶电极对某些代谢物和可溶性酶进行临床测定似乎是相当可行的。通过使用合适的酶,此类装置可以具有高度的特异性,并且能够获得很高的准确度。可以对生理流体进行即时和连续的测定,并且从理论上来说,可以将不良的生理反应降至最低,从而使长期临床监测成为可能。酶电极或许还具有较长的使用寿命,并能满足其他实际要求。

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