Shiloh Y, Naparstek E, Cohen M M
Isr J Med Sci. 1979 Jun;15(6):500-6.
Banding chromosome analysis was performed on 35 bone marrow aspirates from patients with various leukemic and nonleukemic hematologic disorders. Of these, 24 had normal karyotypes, while 11 demonstrated various chromosomal abnormalities. Several of the abnormalities have been previously observed and support the concept of nonrandom involvement of specific chromosomes in aberrations associated with hematologic conditions. In addition, some unique abnormalities were demonstrated in three cases: monosomy 1, trisomy 22, and premature chromosome condensation.
对35例患有各种白血病和非白血病血液系统疾病患者的骨髓穿刺液进行了染色体显带分析。其中，24例核型正常，而11例显示出各种染色体异常。此前已观察到其中一些异常情况，这些异常支持特定染色体非随机参与与血液系统疾病相关的畸变这一概念。此外，在3例病例中发现了一些独特的异常情况：1号染色体单体、22号染色体三体和染色体提前凝聚。
