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胸腺中细胞亚群的分离与鉴定。

Separation and characterization of cell subpopulations in the thymus.

作者信息

Sabolović D, Dumont F

出版信息

Immunology. 1973 Apr;24(4):601-6.

PMID:4574795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1422914/
Abstract

Electrophoretic mobility and PHA responsiveness were studied in mouse thymus cells fractionated on albumin gradient. It was demonstrated that cells with the same electrophoretic mobility may have different buoyant densities. Cortisone-sensitive cells were found to have slow electrophoretic mobility whereas cortisone-resistant PHA responsive cells had fast electrophoretic mobility. Both populations were recovered throughout the gradient but in different proportions.

摘要

对在白蛋白梯度上分离的小鼠胸腺细胞进行了电泳迁移率和对PHA反应性的研究。结果表明，具有相同电泳迁移率的细胞可能具有不同的浮力密度。发现可的松敏感细胞的电泳迁移率较慢，而可的松抗性的PHA反应性细胞具有较快的电泳迁移率。这两种细胞群体在整个梯度中均有回收，但比例不同。

相似文献

1
Separation and characterization of cell subpopulations in the thymus.胸腺中细胞亚群的分离与鉴定。
Immunology. 1973 Apr;24(4):601-6.
2
Electrophoretic analysis of cell subpopulations in the mouse thymus as a function of age.小鼠胸腺细胞亚群随年龄变化的电泳分析。
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3
Lymphocyte populations: separation by discontinuous density gradient centrifugation.淋巴细胞群体：通过不连续密度梯度离心法进行分离。
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[Use of a nonstimulated thymocyte isotope labelling method for determining the DNA sedimentation characteristics in an alkaline saccharose gradient].[使用非刺激胸腺细胞同位素标记法测定碱性蔗糖梯度中的DNA沉降特性]
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Changes of the PHA-responding pool of cells in the thymus after cortisone or x-ray treatment of mice. Evidence for an invese relation between the production of cortical and medullary thymocytes.小鼠经可的松或X射线处理后胸腺中对PHA有反应的细胞池的变化。皮质和髓质胸腺细胞产生之间存在反比关系的证据。
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Lymphocyte populations of AKR-J mice. I. Effect of aging on migration patterns, response to PHA and expression of theta antigen.AKR-J小鼠的淋巴细胞群体。I.衰老对迁移模式、对PHA的反应及θ抗原表达的影响。
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Differentiation-associated cellular complex formation of murine thymocytes with thymic stromal cells.小鼠胸腺细胞与胸腺基质细胞的分化相关细胞复合体形成
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Studies on the isolation of lymphocytes active in cell-mediated immiune responses. II. Identification and recovery of an immunocompetent subpopulation of mouse thymocytes.细胞介导免疫反应中活性淋巴细胞分离的研究。II. 小鼠胸腺细胞免疫活性亚群的鉴定与回收。
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Rate zonal separation of spleen nuclei from normal and Friend virus infected mice.对正常小鼠和感染弗瑞德病毒的小鼠的脾细胞核进行速率区带分离。
Res Commun Chem Pathol Pharmacol. 1972 Mar;3(2):403-15.

引用本文的文献

1
Electrophoretic mobility of mouse T-cell hybrids.小鼠T细胞杂交体的电泳迁移率
Br J Cancer. 1981 Nov;44(5):692-9. doi: 10.1038/bjc.1981.255.
2
Electrophoretic analysis of cell subpopulations in the mouse thymus as a function of age.小鼠胸腺细胞亚群随年龄变化的电泳分析。
Immunology. 1974 May;26(5):1051-7.
3
Electrophoretic mobility and surface immunoglobin of albumin gradient fractionated mouse spleen cells.白蛋白梯度分离的小鼠脾细胞的电泳迁移率和表面免疫球蛋白
Immunology. 1975 Apr;28(4):731-9.
4
A method for the separation of lymphocytes and plasma cells from the human palatine tonsil using sedimentation in an isokinetic gradient of Ficoll in tissue culture medium.一种在组织培养基中利用Ficoll等速梯度沉降从人腭扁桃体分离淋巴细胞和浆细胞的方法。
Immunology. 1975 Jan;28(1):161-70.
5
Distribution of electrophoretic mobilities of mouse thymocyte subpopulations in the presence of tumour cells.在肿瘤细胞存在的情况下小鼠胸腺细胞亚群的电泳迁移率分布
Immunology. 1975 Nov;29(5):893-902.
6
Characterization of cell subpopulations of the thymus by a hydrophobic fluorescent probe: 1-anilino-8-naphthalene sulphonate.用疏水荧光探针1-苯胺基-8-萘磺酸盐对胸腺细胞亚群进行表征
Clin Exp Immunol. 1977 Nov;30(2):283-8.
7
Physical subpopulations of mouse thymocytes: changes during regeneration subsequent to cortisone treatment.小鼠胸腺细胞的物理亚群：可的松治疗后再生过程中的变化。
Immunology. 1978 May;34(5):841-52.
8
Immunological characteristics of lymphoblasts and lymphocytes in acute lymphoblastic leukaemia in children.儿童急性淋巴细胞白血病中淋巴母细胞和淋巴细胞的免疫学特征
Clin Exp Immunol. 1977 Aug;29(2):220-8.

本文引用的文献

1
An apparatus for microelectrophoresis of small particles.一种用于小颗粒微电泳的装置。
Nature. 1958 Sep 6;182(4636):642-4. doi: 10.1038/182642a0.
2
Loss of thymus-distinctive serological characteristics in mice under certain conditions.在某些条件下小鼠胸腺独特血清学特征的丧失。
Science. 1967 Mar 3;155(3766):1114-6. doi: 10.1126/science.155.3766.1114.
3
Two populations of small lymphocytes.两群小淋巴细胞。
J Cell Biol. 1968 Apr;37(1):196-9. doi: 10.1083/jcb.37.1.196.
4
Cellular differentiation in the thymus. 3. Surface properties of rat thymus and lymph node cells separated on density gradients.胸腺中的细胞分化。3. 经密度梯度分离的大鼠胸腺和淋巴结细胞的表面特性。
J Exp Med. 1970 Dec 1;132(6):1107-21. doi: 10.1084/jem.132.6.1107.
5
Evidence for a small pool of immunocompetent cells in the mouse thymus.小鼠胸腺中存在少量免疫活性细胞的证据。
Exp Cell Res. 1969 Oct;57(2):185-92. doi: 10.1016/0014-4827(69)90140-2.
6
Evidence for subpopulation of mature lymphocytes within mouse thymus.小鼠胸腺内成熟淋巴细胞亚群的证据。
Nat New Biol. 1971 Feb 10;229(6):182-4. doi: 10.1038/newbio229182a0.
7
In vitro stimulation of mouse thymus cells by PHA and allogeneic cells.用PHA和同种异体细胞对小鼠胸腺细胞进行体外刺激。
Cell Immunol. 1971 Aug;2(4):285-99. doi: 10.1016/0008-8749(71)90063-3.
8
Antigenic change and cell maturation in murine thymocytes.小鼠胸腺细胞中的抗原性变化与细胞成熟
Cell Immunol. 1970 Nov;1(5):536-44. doi: 10.1016/0008-8749(70)90040-7.
9
Separation of stages in the development of the "T" cells involved in cell-mediated immunity.参与细胞介导免疫的 “T” 细胞发育阶段的分离。
J Exp Med. 1972 Jun 1;135(6):1375-91. doi: 10.1084/jem.135.6.1375.
10
The separation of sub-populations of T and B lymphocytes.T淋巴细胞和B淋巴细胞亚群的分离。
Eur J Immunol. 1972 Aug;2(4):313-9. doi: 10.1002/eji.1830020404.