Essery J M, Doyle T W
J Antibiot (Tokyo). 1979 Mar;32(3):247-9. doi: 10.7164/antibiotics.32.247.
The conversion of epsilon-rhodomycinone to its 11-methyl ether via selective hydrolysis of the 4,6,7,11-tetraacetate is described. This series of reactions was used as a model for the conversion of carminomycin to its 11-methyl ether. The anti-tumor activity of the latter compound was less than that of both carminomycin and its 4-methyl ether (daunomycin).
描述了通过4,6,7,11 - 四乙酸酯的选择性水解将ε - 玫瑰霉素酮转化为其11 - 甲基醚的过程。这一系列反应被用作将洋红霉素转化为其11 - 甲基醚的模型。后一种化合物的抗肿瘤活性低于洋红霉素及其4 - 甲基醚（柔红霉素）。
