抗叶酸类似物的噬菌体T4突变体的分离与鉴定 - Suppr

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Isolation and characterization of mutants of bacteriophage T4 resistant to folate analogs.

作者信息

Johnson J R, Hall D H

出版信息

Virology. 1973 Jun;53(2):413-26. doi: 10.1016/0042-6822(73)90221-3.

DOI:10.1016/0042-6822(73)90221-3

PMID:4576345

Abstract

摘要

相似文献

Isolation and characterization of mutants of bacteriophage T4 resistant to folate analogs.抗叶酸类似物的噬菌体T4突变体的分离与鉴定

Virology. 1973 Jun;53(2):413-26. doi: 10.1016/0042-6822(73)90221-3.

Levels of dihydrofolate reductase and thymidylate synthetase in strains of Streptococcus faecium resistant to substituted pyrimidines, triazines and MTX.对取代嘧啶、三嗪和甲氨蝶呤耐药的粪肠球菌菌株中二氢叶酸还原酶和胸苷酸合成酶的水平

Ann N Y Acad Sci. 1971 Nov 30;186:182-4.

Dihydrofolate reductase and thymidylate synthetase in strains of Streptococcus faecium resistant to pyrimethamine, chlorguanide triazine, trimethoprim, and amethopterin.对乙胺嘧啶、氯胍三嗪、甲氧苄啶和氨甲蝶呤耐药的屎肠球菌菌株中的二氢叶酸还原酶和胸苷酸合成酶

Arch Biochem Biophys. 1972 Jan;148(1):1-9. doi: 10.1016/0003-9861(72)90108-7.

Identity of genes coding for soluble and structural dihydrofolate reductases in bacteriophage T4.噬菌体T4中编码可溶性和结构二氢叶酸还原酶的基因的鉴定。

J Virol. 1971 Apr;7(4):531-3. doi: 10.1128/JVI.7.4.531-533.1971.

Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues.各类叶酸类似物对细菌和脊椎动物来源的二氢叶酸还原酶的抑制机制。

Biochim Biophys Acta. 1986 Feb 14;869(3):275-85. doi: 10.1016/0167-4838(86)90067-1.

Two different effects of mutation on the binding of folate antagonists by a microbial dihydrofolate reductase.突变对微生物二氢叶酸还原酶结合叶酸拮抗剂的两种不同影响。

Biochim Biophys Acta. 1973 Mar 15;302(1):13-23. doi: 10.1016/0005-2744(73)90003-x.

Functions of baseplate components in bacteriophage T4 infection. I. Dihydrofolate reductase and dihydropteroylhexaglutamate.

Virology. 1973 Oct;55(2):380-90. doi: 10.1016/0042-6822(73)90178-5.

Novel mechanism of resistance to folate analogues: ribonucleoside diphosphate reductase deficiency in bacteriophage T4.对叶酸类似物耐药的新机制：噬菌体T4中的核糖核苷二磷酸还原酶缺陷

Antimicrob Agents Chemother. 1976 Feb;9(2):292-300. doi: 10.1128/AAC.9.2.292.

Dihydrofolate reductases in some folate-requiring bacteria with low trimethoprim susceptibility.一些对甲氧苄啶敏感性较低的需叶酸细菌中的二氢叶酸还原酶。

Antimicrob Agents Chemother. 1978 Jul;14(1):112-7. doi: 10.1128/AAC.14.1.112.

[In vitro sensitivity of Plasmodium falciparum to anti-folinic agents (trimethoprim, pyrimethamine, cycloguanil): a study of 29 African strains].恶性疟原虫对抗亚叶酸剂（甲氧苄啶、乙胺嘧啶、环氯胍）的体外敏感性：对29株非洲菌株的研究

Bull Soc Pathol Exot. 1997;90(2):90-3.

引用本文的文献

Bacteriophage T4 genome.噬菌体T4基因组。

Microbiol Mol Biol Rev. 2003 Mar;67(1):86-156, table of contents. doi: 10.1128/MMBR.67.1.86-156.2003.

An N-terminal mutation in the bacteriophage T4 motA gene yields a protein that binds DNA but is defective for activation of transcription.噬菌体T4 motA基因的N端突变产生一种能结合DNA但在转录激活方面存在缺陷的蛋白质。

J Bacteriol. 1996 Nov;178(21):6133-9. doi: 10.1128/jb.178.21.6133-6139.1996.

Distribution and characterization of mutations induced by nitrous acid or hydroxylamine in the intron-containing thymidylate synthase gene of bacteriophage T4.亚硝酸或羟胺诱导噬菌体T4含内含子胸苷酸合成酶基因突变的分布与特征分析

Biochem Genet. 1993 Dec;31(11-12):507-20. doi: 10.1007/BF02426882.

Dual functions of bacteriophage T4D gene 28 product: structural component of the viral tail baseplate central plug and cleavage enzyme for folyl polyglutamates. II. Folate metabolism and polyglutamate cleavage activity of uninfected and infected Escherichia coli cells and bacteriophage.噬菌体T4D基因28产物的双重功能：病毒尾基板中央栓的结构成分和叶酰聚谷氨酸的裂解酶。II. 未感染和感染的大肠杆菌细胞及噬菌体的叶酸代谢和聚谷氨酸裂解活性

J Virol. 1981 Dec;40(3):645-56. doi: 10.1128/JVI.40.3.645-656.1981.

Genetic evidence for physical interactions between enzymes of nucleotide synthesis and proteins involved in DNA replication in bacteriophage T4.噬菌体T4中核苷酸合成酶与参与DNA复制的蛋白质之间物理相互作用的遗传证据。

Genetics. 1984 Jul;107(3):343-53. doi: 10.1093/genetics/107.3.343.

Control of early gene expression of bacteriophage T4: involvement of the host rho factor and the mot gene of the bacteriophage.噬菌体T4早期基因表达的调控：宿主rho因子和噬菌体mot基因的作用

J Virol. 1980 Feb;33(2):724-32. doi: 10.1128/JVI.33.2.724-732.1980.

Characterization of new regulatory mutants of bacteriophage T4.噬菌体T4新型调控突变体的特性分析

J Virol. 1974 Mar;13(3):666-76. doi: 10.1128/JVI.13.3.666-676.1974.

Escherichia coli Rho factor is involved in lysis of bacteriophage T4-infected cells.大肠杆菌Rho因子参与噬菌体T4感染细胞的裂解过程。

Genetics. 1985 Oct;111(2):197-218. doi: 10.1093/genetics/111.2.197.

Antimicrob Agents Chemother. 1976 Feb;9(2):292-300. doi: 10.1128/AAC.9.2.292.

Bacteriophage T4 baseplate components. III. Location and properties of the bacteriophage structural thymidylate synthetase.噬菌体T4基板组件。III. 噬菌体结构胸苷酸合成酶的定位与特性

J Virol. 1975 Dec;16(6):1409-19. doi: 10.1128/JVI.16.6.1409-1419.1975.

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