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实验性钩虫病期间的肠道肥大细胞

Intestinal mast cells during experimental ancylostomiasis.

作者信息

Vardhani V, Johri G N

出版信息

J Helminthol. 1979 Mar;53(1):35-9. doi: 10.1017/s0022149x00005708.

DOI:10.1017/s0022149x00005708
PMID:458129
Abstract

The alterations of mast cell counts induced in the gut of swiss albino mice by infection with Ancylostoma caninum larvae have been studied, both in single and multiple infections. It was found that mast cell rise was greater in females than males. In singly infected animals, mast cell increase was influenced by the infective dose of inoculated larvae. In case of repeatedly infected mice, mast cell counts were decreased because of their earlier degranulation.

摘要

研究了感染犬钩虫幼虫后,瑞士白化小鼠肠道中肥大细胞数量的变化,包括单次感染和多次感染的情况。结果发现,雌性小鼠的肥大细胞增多比雄性更明显。在单次感染的动物中,肥大细胞的增加受接种幼虫感染剂量的影响。在反复感染的小鼠中,由于肥大细胞较早脱颗粒,其数量会减少。

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