哺乳动物促性腺激素和同源促性腺激素对切除垂体的食用蛙中δ5-3β-羟基类固醇脱氢酶（HSD）活性的影响。
The effect of mammalian gonadotropins and homologous gonadotropins on the activity of delta 5-3 beta-hydroxy-steroid-dehydrogenase (HSD) in hypophysectomized Rana esculenta.
作者信息
Bellini-Cardellini L, Palatroni P, Gobbetti A
出版信息
Basic Appl Histochem. 1979;23(1):45-51.
Mammalian gonadotropins and partially purified gonadotropins (FSH and LH) from an amphibian (Rana esculenta) were used to investigate their action on enzymatic activity of delta 5-3 beta-HSD in male and female hypophysectomized Rana esculenta in stage of genital activity (October) and in stasis or hibernation stage (January). Amphibian and equine LH stimulate delta 5-3 beta-HSD activity especially in females hypophysectomized in the stage of genital activity, while ovine FSH action is very low and amphybian FSH practically inactive. The present data suggested that control of gonadotropic activity in the reproductive cycle in Rana esculenta is LH-dependent.
利用哺乳动物促性腺激素以及来自两栖动物（食用蛙）的部分纯化促性腺激素（促卵泡激素和促黄体生成素），研究它们对处于生殖活动期（10月）、静止期或冬眠期（1月）的雌雄去垂体食用蛙中δ5-3β-羟类固醇脱氢酶（delta 5-3 beta-HSD）酶活性的作用。两栖动物和马的促黄体生成素能刺激δ5-3β-羟类固醇脱氢酶的活性，尤其是在生殖活动期去垂体的雌性动物中，而绵羊促卵泡激素的作用非常低，两栖动物促卵泡激素实际上无活性。目前的数据表明，食用蛙生殖周期中促性腺激素活性的控制依赖于促黄体生成素。
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