Straznicky C, Glastonbury J
J Embryol Exp Morphol. 1979 Apr;50:111-22.
Unilateral left tectal ablation was carried out in Xenopus between stage 48 and 1 month after metamorphosis. Six to 12 weeks after metamorphosis the retinal projection from the right eye was examined with the use of [3H]proline autoradiography. The autoradiographs indicated that optic fibres whose tectal target was destroyed recrossed to the ipsilateral tectum and basal optic nucleus via the posterior and pretectal commissures. No anomalous recrossing occurred if the tectal ablation was carried out at stage 58 or later. The aberrant optic fibres were restricted to the rostrolateral and central parts of the ipsilateral tectum and they terminated in a discontinuous manner. It is concluded that available surfaces serving as contact guidance cues are needed to direct aberrant optic fibres to the ipsilateral tectum.
在非洲爪蟾变态后48期至1个月期间进行单侧左顶盖切除。变态后6至12周，利用[3H]脯氨酸放射自显影术检查右眼的视网膜投射。放射自显影片显示，其顶盖靶点被破坏的视神经纤维通过后连合和顶盖前连合重新交叉至同侧顶盖和基底视核。如果在58期或更晚进行顶盖切除，则不会发生异常交叉。异常的视神经纤维局限于同侧顶盖的 rostrolateral 和中央部分，并且它们以不连续的方式终止。得出的结论是，需要可用的表面作为接触引导线索，以将异常的视神经纤维引导至同侧顶盖。
