接种阿留申病病毒的浅色和蓝宝石色水貂的抗体形成细胞及血清溶血素反应
Antibody-forming cells and serum hemolysin responses of pastel and sapphire mink inoculated with Aleutian disease virus.
作者信息
Lodmell D L, Bergman R K, Hadlow W J
出版信息
Infect Immun. 1973 Nov;8(5):769-74. doi: 10.1128/iai.8.5.769-774.1973.
Abstract
The effect of Aleutian disease virus (ADV) on serum hemolysin titers and antibody-forming cells in lymph nodes and spleens of sapphire and pastel mink inoculated with goat erythrocytes (G-RBC) was investigated. ADV injected 1 day after primary antigenic stimulation with G-RBC did not depress the immune responses of either color phase for a period of 26 days. However, when G-RBC were injected 47 days after ADV, both the number of antibody-forming cells and hemolysin titers were more markedly depressed in sapphire than in pastel mink. The results are discussed in relation to the greater susceptibility of sapphire mink and the variable susceptibility of pastel mink to the Pullman isolate of ADV.
摘要
研究了阿留申病病毒（ADV）对用山羊红细胞（G-RBC）接种的蓝宝石色和淡紫色水貂血清溶血素滴度以及淋巴结和脾脏中抗体形成细胞的影响。在用G-RBC进行初次抗原刺激1天后注射ADV，在26天的时间内，两种毛色阶段的免疫反应均未受到抑制。然而，当在ADV注射47天后注射G-RBC时，蓝宝石色水貂的抗体形成细胞数量和溶血素滴度比淡紫色水貂受到的抑制更为明显。结合蓝宝石色水貂对ADV普尔曼分离株的更高易感性以及淡紫色水貂的可变易感性对结果进行了讨论。
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本文引用的文献
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