高渗氯化钠胃内负荷对甲状腺切除的青春期前大鼠的影响。
The effects of stomach loads of hypertonic NaCl on thyroidectomized prepubescent rats.
作者信息
Kozub F J, Lamm R
出版信息
J Gen Psychol. 1979 Apr;100(2d Half):313-7. doi: 10.1080/00221309.1979.9710962.
PMID:458427
Abstract
Prepubescent male and female rats (N = 56) were surgically thyroidectomized and given stomach loads of .9% or 6.0% NaCl. The 6.0% NaCl, thyroidectomized S s responded by decreasing food intake and losing weight 24 hours after loading. Normal S s did not, and no sex difference was found. The .9% NaCl thyroidectomized S s drank significantly less than the normals. The results were interpreted in terms of thyroid hormone activity which affects renal function.
摘要
对青春期前的雄性和雌性大鼠（N = 56）进行手术切除甲状腺，并给予0.9%或6.0%的氯化钠胃内负荷。给予6.0%氯化钠后，甲状腺切除的受试动物在负荷后24小时通过减少食物摄入量和体重减轻做出反应。正常受试动物则没有，且未发现性别差异。给予0.9%氯化钠后，甲状腺切除的受试动物饮水量明显低于正常动物。结果根据影响肾功能的甲状腺激素活性进行了解释。
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