Young L A
J Pediatr Ophthalmol Strabismus. 1979 Mar-Apr;16(2):105-7. doi: 10.3928/0191-3913-19790301-05.
The observation in this study of 33 pediatric patients with thyroid disfunction supports the view that ocular changes are uncommon in this age group. If ophthalmopathy does occur, it is mild. No patient was found to have clinical myopathy, corneal involvement, or visual loss. B Scan Ultrasonography demonstrated extraocular muscle involvement despite the absence of clinical signs and symptoms of myopathy. There was no HLA antigen prevalence in those patients with ophthalmopathy as compared with those free of ocular change. It is suggested that the conservative medical management of the pediatric group with thyroid disease may account for the low incidence of severe ocular changes.
本研究对33例甲状腺功能障碍儿科患者的观察结果支持以下观点:该年龄组眼部变化并不常见。如果确实发生眼病,也是轻微的。未发现患者有临床肌病、角膜受累或视力丧失。B超检查显示,尽管没有肌病的临床体征和症状,但存在眼外肌受累情况。与无眼部变化的患者相比,眼病患者中未发现HLA抗原流行情况。有人认为,儿科甲状腺疾病组的保守药物治疗可能是严重眼部变化发生率低的原因。